Body mass index may be the major determining factor of systolic and diastolic blood pressure in the human body

Mehmet Rami Helvaci (1)
Mehmet Duru (2)
Atilla Yalcin (1)
Orhan Ekrem Muftuoglu (1)
Abdulrazak Abyad (3)
Lesley Pocock (4)

(1) Specialist of Internal Medicine, MD
(2) Specialist of Emergency Medicine, MD
(3) Middle-East Academy for Medicine of Aging, MD
(4) medi-WORLD International

Corresponding author:
Prof Dr Mehmet Rami Helvaci,
ALANYA, Antalya, TurkeyPhone: 00-90-506-4708759
Email: mramihelvaci@hotmail.com

Received: December 2020; Accepted: January 2021; Published: February 1, 2021
Citation: Mehmet Rami Helvaci et al. Body mass index may be the major determining factor of systolic and diastolic blood pressure in the human body. Middle East Journal of Nursing 2021; 15(1): 12-17.DOI: 10.5742/MEJN2021.93797

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ABSTRACT

Background: We tried to understand possible effects of sickle cell diseases (SCD) on metabolic parameters including systolic and diastolic blood pressure (BP) in the body.

Methods: All patients with the SCD and age and gender-matched control cases were included into the study.

Results: We studied 363 patients with the SCD (194 males) and 255 control cases (136 males), totally. Mean ages of the SCD patients were similar in males and females (31.1 versus 31.0 years, respectively, p>0.05). Although the mean body weight and body mass index (BMI) were significantly suppressed in the SCD patients (59.9 versus 71.5 kg and 21.9 versus 25.6 kg/m2, respectively, p= 0.000 for both), the mean body heights were similar in both groups (164.9 versus 167.0 cm, p>0.05). Parallel to the suppressed mean body weight and BMI, fasting plasma glucose (92.8 versus 97.6 mg/dL, p= 0.005), total cholesterol (121.4 versus 165.0 mg/dL, p= 0.000), low density lipoproteins (70.4 versus 102.4 mg/dL, p= 0.000), and high density lipoproteins (26.0 versus 39.6 mg/dL, p= 0.000) were all lower in the SCD patients, significantly. Similarly, both systolic (115.2 versus 122.6 mmHg, p= 0.000) and diastolic BP (73.0 versus 86.6 mmHg, p= 0.000) were also lower in them, significantly. Interestingly, only the mean triglycerides value was higher in the SCD patients (129.4 versus 117.3 mg/dL, p= 0.000), significantly. Similarly, mean alanine aminotransferase value was not suppressed in them, too (27.4 versus 27.3 U/L, p>0.05).

Conclusion: BMI may be the major determining factor of systolic and diastolic BP in the human body.

Key words: Body mass index, systolic blood pressure, diastolic blood pressure, metabolic syndrome, sickle cell diseases