| August
2021
- Volume 15, Issue 3
Blood
Glucose Control and Surgical Site Infections in Cancer Patients:
A Literature Review
Layla Mahmoud Mohamed
(1)
Bridget Stirling (2)
Kathleen Benjamin (3)
Jessie Johnson (4)
(1) Layla Mahmoud Mohamed RN, BSN,
MN email lomhamed@hamad.qa
(2) RN, BScN, MPH, PhD
(3) RN, BScN, MScN, PhD, Adjunct, University of Calgary
(4) RN, BScN, MN, PhD, Faulty of Nursing, University of Calgary
in Qatar
Corresponding author:
Layla Mahmoud Mohamed RN, BSN, MN
Email: lomhamed@hamad.qa
Received: June 2021; Accepted: July
2021; Published: August, 2021
Citation: Layla Mahmoud Mohamed et al. Blood Glucose Control
and Surgical Site Infections in Cancer Patients: A Literature
Review. Middle East Journal of Nursing 2021; 15(3): 35-43.DOI:
10.5742/MEJN2021.9378013
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ABSTRACT
Background:
Surgical site infections (SSI) are the most common acquired
infection during hospitalization and a major cause of morbidity,
mortality, increased health care costs and delays in treatments
for cancer patients.
Objective: The objective of
this literature review was to gain a better understanding
of the relationship between uncontrolled blood glucose and
the odds of developing a SSI among cancer patients.
Interventions / Methods: A
database search (which engaged PubMed, Medline, Cumulative
Index to Nursing and Allied Health Literature and The Cochrane
Database of Systematic Reviews) was completed using the key
words: ‘surgical site infection’ or ‘surgical
wound infection’ OR ‘SSI’ AND cancer or neoplasms
OR oncology OR tumor OR malignancy AND diabetes OR hyperglycemia
AND risk factors. Twenty-seven studies met the inclusion criteria
to be included in this review.
Results: The odds ratio for
history of diabetes or hyperglycemia and SSI following cancer
surgery varied across studies. This is likely explained in
part by the fact that some types of surgery are more invasive
than others, are more lengthy, and involve areas of the body
that are more prone to infection. The study with the highest
rate of SSI (62.1%) was among patients with oral cancer and
the study with the lowest rate of SSI (3.1%) was among patients
with spinal cancer.
Conclusion: The literature
review results suggested an association between SSI and patients
with a history of diabetes mellitus or hyperglycemia.
Key Words: Diabetes, cancer, literature review, surgical
site infections, surgery, glucose
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